367-368. Embelin has been isolated from the aerial parts. Flowers bisexual, usually 5-merous, dirty pink or lilac, or purplish, corolla lobes pinkish to whitish inside, throat dark purple; calyx campanulate, 5-lobed, lobes triangular, up to 1 mm × 0.6 mm, normally glabrous; corolla cylindrical to bell-shaped, 5-17 mm × 2-5 mm, throat and inside of tube densely long-hairy, lobes 5, oblong to triangular, 1-3 mm × 1.5-3 mm, margins wavy, inflexed; stamens 5, inserted in the middle of the tube, included, anthers 2-2.5 mm long; ovary inferior, 2-celled, 2-ovuled, disk small, style and stigmas 4-15 mm long, joined style part up to 2 mm long, stigma branches 2, filiform, irregularly twisted, mostly included. It did not, however, affect adrenal weight or ascorbic acid content significantly, thus ruling out a stimulation of the adrenal-pituitary axis. The northeastern region of India constitutes one of the biodiversity hotspots of the world. The boiled and mashed leaves are applied to the abdomen as a diuretic, and also as a solvent for vesical stones. P. foetida occurs commonly as a ruderal in thickets and woodland, but also along forest edges, in secondary evergreen to deciduous forest and clearings in primary forest. Revised reprint. It also inhibited the elevation of serum orosomucoid levels in rats, suggesting the possibility of the presence of disease-modifying antirheumatic activity. The leaves are antirheumatic. Monoterpenes such as linalol constitute the major components in the oil. As per the properties and functions of the herb it is used in healing the problems related to intestinal health (particularly anti-diarrheal and anti-dysentery) and as a support for male health. The main use The main use of the plant is for arthritis and:rheumatic disorders. The leaves can be mixed in omelettes as well for intestinal mucus. The percentage of antioxidant activity for all extract samples using both assays was between 58 and 80%. asperuloside, scandoside and paederoside were isolated from the aerial parts of P. foetida . Linalool is the major component of the oil obtained from the stem, leaf and flower, together with a-terpineol and geranio1.2 The leaf and stem also contain hentriacontane, hentriacontanol and ceryl alcohol, 2,3-dihydrobenzofuran, benzofuran and the sulphur-containing compounds dimethyl sulphide and dimethyl trisulphide. In this study, experiments were designed to develop regeneration protocols for the propagation as well as conservation of a rare medicinal plant, Paederia foetida (L.) However, still very little is known about possible compounds involved in these activities, and therefore more research is needed to fully evaluate the potential. The leaves are antirheumatic. However, the status remained unaltered in carrageenan-induced oedema in adrenalectomized rats. ... Paederia foetida L. . A slender, perennial, stinking twiner, 1.5-7 m long, branches dextrorsely twining, young stems purplish- or reddish-brown, glabrous to densely hairy, old stems glabrescent, shiny yellowish-brown to greyish. Paederia foetida L. is an important medicinal herb harboring lots of essential drug producing metabolites and the plant has been going to be endangered due to lack of proper strategies for conservation. In India, the juice of the root is also prescribed in piles, inflammation of the spleen, and pain in the chest and liver. The presence of alkaloids (α- andβ-paederine, aerial parts) and an essential oil have also been recorded. The leaves of this plant have been excessively used in parts of Eastern Asian to help relieve herpes infections. Antiarthritic activity: Paederia foetida extract was tested for its effect on osteoarthritis-like lesions induced in the knee joints of rabbits by ananase (the proteolytic enzyme from pineapple). 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